Welcome to ROSBase

Reactive Oxygen Species (ROS) are mostly free radicals derived from molecular oxygen; those are highly reactive and capable of oxidizing a large number of molecules. The most common ROS’s found in the cell organelles from plant and animal cells are hydrogen peroxides (H₂O₂), superoxide (O₂⁻), hydroxyl radical (^•OH), singlet oxygen (¹O₂), etc. The cell organelles involved in ROS production are mitochondria, endoplasmic reticulum (ER), peroxisomes, cytoplasm, nucleus, cell membrane, vacuole, chloroplast, lysosomes, phagosomes, etc. ROS are prominently known for their physiological role within the cell, maintaining homeostasis. However, the homeostasis within the cell can be disrupted and may lead to different diseases. The ROS Producing and Scavenging Protein - DataBase (ROSBase) carries information about ROS related proteins. The database is developed to assist in understanding ROS associated proteins, their pertinent processes, and the associated disorders.

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